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Working and treatment of
Citalopram – Celexa |
Citalopram–Celexa is an antidepressant medication used to treat
depression.
In depression, there is a deficiency of several neurotransmitters,
including serotonin (5-HT), norepinephrine and dopamine. According
to the tests on Celexa, antidepressants act by increasing the
concentration of neurotransmitters at the synapse. In general there
is a period of two to three weeks prior to the effective action of
the product as the tests suggest. This delay is due to the fact that
although antidepressants increase synaptic concentration from the
outset by inhibiting the reuptake ago feedback on the
self-pre-synaptic receptors that inhibit the release.
After two or three weeks of continous use of Celexa, there is a
desensitization of these self-presynaptic receptors and the release
rises, and the therapeutic effect. Inhibitors, serotonin reuptake-norepinephrine
or SNRIs as they are called, are taken to selectively inhibit
increasing levels of norepinephrine and serotonin. They will not,
therefore, unlike tri-cyclic antidepressants, action on dopamine.
This inhibition causes an increase in the synaptic concentration of
these neurotransmitters. As the tests confirmed, after a long term
use of Citalopram we observed a "down regulation" in post
synaptiques 5HT2A receptors in the β serotonin and norepinephrine in
post synaptiques, receivers being too many in the depression.
Citalopram belongs to a group of antidepressants with a dual action
at the level of serotonin and norepinephrine, which is associated
with an increase in energy and motivation. Effexor is a response
rate and remission of the disease most pronounced in the first few
weeks of treatment with SSRIs. It has improved the profile of side
effects compared with SSRIs. While stimulating the 5-HT1A receptor,
Serzone blocks the 5-HT2 receptors and avoid the side effects
associated with restlessness, insomnia and decreased libido.
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